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Query Open Targets Platform API for Locus-to-Gene (L2G) predictions

Source: R/annotate.R
query_ot_api_v2g.Rd

This function retrieves L2G predictions from credible sets containing the specified variant. It replaces the deprecated V2G functionality from the old Open Targets Genetics API.

Usage

query_ot_api_v2g(variant_id = "19_44908822_C_T", pageindex = 0, pagesize = 20)

Arguments

variant_id

A string representing the variant ID in format "CHR_POS_REF_ALT" (e.g., "19_44908822_C_T") or an rsID (e.g., "rs123456").

pageindex

Pagination index (currently unused in new API structure).

pagesize

Pagination size (currently unused in new API structure).

Value

A list containing L2G predictions and associated data from credible sets.

Note

This function has been migrated from the deprecated Open Targets Genetics API to the new Open Targets Platform API. The functionality has changed from direct variant-to-gene mapping to locus-to-gene predictions via credible sets.

Examples

if (FALSE) { # \dontrun{
  # Query by variant ID
  result <- query_ot_api_v2g("19_44908822_C_T")
  
  # Query by rsID  
  result <- query_ot_api_v2g("rs123456")
} # }